Reanalysis of cancer drugs: old drugs, new tricks.
نویسندگان
چکیده
George F. Vande Woude, Gary J. Kelloff, Raymond W. Ruddon, Han-Mo Koo, Caroline C. Sigman, J. Carl Barrett, Robert W. Day, Adam P. Dicker, Robert S. Kerbel, David R. Parkinson, and William J. Slichenmyer Van Andel Research Institute, Grand Rapids, Michigan; Division of Cancer Treatment and Diagnosis and Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; Johnson & Johnson Corporation, New Brunswick, New Jersey; CCS Associates, Mountain View, California; Fred Hutchinson Cancer Research Center, Seattle, Washington; Thomas Jefferson University Hospital, Philadelphia, Pennsylvania; Toronto-Sunnybrook Regional Cancer Center, Toronto, Ontario, Canada; Amgen Inc., Thousand Oaks, California; and Pfizer Global Research and Development, New London, Connecticut
منابع مشابه
Special Review Reanalysis of Cancer Drugs: Old Drugs, New Tricks
George F. Vande Woude, Gary J. Kelloff, Raymond W. Ruddon, Han-Mo Koo, Caroline C. Sigman, J. Carl Barrett, Robert W. Day, Adam P. Dicker, Robert S. Kerbel, David R. Parkinson, and William J. Slichenmyer Van Andel Research Institute, Grand Rapids, Michigan; Division of Cancer Treatment and Diagnosis and Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; Johnson & Johnson...
متن کاملCancer drug discovery by repurposing: teaching new tricks to old dogs.
Progressively increasing failure rates, high cost, poor bioavailability, poor safety, limited efficacy, and a lengthy design and testing process associated with cancer drug development have necessitated alternative approaches to drug discovery. Exploring established non-cancer drugs for anticancer activity provides an opportunity rapidly to advance therapeutic strategies into clinical trials. T...
متن کاملIntra-articular Injections for Osteoarthritis: From Bench to Bedside, can we Teach Old Drugs New Tricks?
The two articles in this month’s press of The Journal of Arthritis, one by Ekinci et al. titled ‘A New Treatment Option in Osteoarthritis: Prolotherapy Injections’ and the other by Senatorov et al. titled ‘Clinical Outcome of Hylan G-F 20 Injections in Shoulder and Hip Osteoarthritis: A Retrospective Review’ raise several important points surrounding the topic of intra-articular injections [1,2...
متن کاملOld Drugs, New Tricks Using Genetically Sensitized Yeast to Reveal Drug Targets
A study in this issue of Cell illustrates the power of applying genomic approaches with model systems to characterize the biological activity of small molecules and to identify their cellular targets, which can clarify the mode of action of human therapeutics.
متن کاملAttitude of Iranian Medical Oncologists Toward Economic Aspects, and Policy-making in Relation to New Cancer Drugs
Background Although medical oncologists can have an important role in controlling the cost of cancer treatment, there is little information about their attitudes toward the cost of cancer treatment and the impact of cost on their treatment recommendations, especially in low- and middle-income countries (LMICs). In this study, we assessed the attitude of Iranian medical oncologists toward some e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 10 11 شماره
صفحات -
تاریخ انتشار 2004